The PRCC, in collaboration with health and human community-based organizations, faith-based groups, and AoU partners, including the IL Precision Medicine Consortium and NNLM, proposes to develop and implement culturally, linguistically- and health literacy-appropriate community outreach and education programs targeting Latino families, the elderly, 91, the disability community, and other vulnerable populations. The project activities follow community engagement and empowerment approaches with the main goal to support the work of the NNLM while facilitating recruitment and retention of participants to that will ultimately contribute to meeting the national program goal of enrolling one-million persons of diverse backgrounds that will participate in future studies to advance personalized medicine. During January 1, 2021 to April 30, 2021, the project will develop bilingual educational materials, conduct health education events and engage in other community outreach activities, including linkages with MedlinePlus and MedlinePlus en Espanol, a consumer friendly, evidence-based health information from the National Library of Medicine.