This award would partially fund Phase I of a Medicinal Chemistry Cheminformatics Concentration Track for students enrolled in a school of pharmacy. In Phase I students will learn to use literature NLM and open data sources DNDi/WHO to curate and analyze early drug discovery chemical data focusing on neglected diseases. Student outcomes will include mastery in the use of cheminformatics software Optibrium/StarDrop for data management, data visualization and predictive calculations. Phase II will introduce students to the chemical synthesis of new drug leads based on their Phase I data. The synthetic steps and biological activity results of all compounds will be shared 94ly via an open source electronic laboratory notebook ELN. The impact of the proposal is three-fold: 1 increase health care personnel training in pharma-relevant informatics, 2 apply data management skills to curate analyze and use a cheminformatics database and 3 synthesize new chemical compounds aimed at treating neglected diseases. The diseases targeted are Leishmaniasis and American Trypanosomiasis.

Project Details

Organization Name

MCPHS, Worcester - Blais Family Library

Organization Type
Academic institution
Health sciences library
Project Lead


Start Date
May 1, 2020
End Date
April 30, 2021
Funding Amount
Data Resource or Tool Developer
Educator, College & Post-grad
Health care Provider
Library or Information Professional
Student, College & Post-grad
Adults (19-64 yrs.)